Welcome to the Hasson Lab website


The Extracellular Matrix as an Active Tissue Component

The cells within our bodies are embedded with extracellular matrix (ECM). Although previously thought to be rather inert and primarily to provide structural support to the cells, it is now clear that the matrix participates and regulates numerous processes including proliferation, differentiation, migration, and adhesion at the cellular level as well as patterning and morphogenesis at the tissue level.


Our aim: to study the tight crosstalk between the cells and their surrounding environment, in both development, health, and disease.

In the lab, we use several model systems, to dissect how connective tissue resident cells develop, how they participate in stress-induced ECM remodeling, and how can we use our knowledge and expertise in this field to develop new therapeutic approaches for related pathologies.

Our work combines in-vivo experiments and mouse genetics, cell cultures, and computational tools for bioinformatics and image analysis.

 

To read more about Our Research

We are located at the Rappaport Faculty of Medicine of the Technion – Israel Institute of Technology. Contact us